The International Journal of Epidemiology today published a combined data analysis from a multi national population-based case-control study of glioma and meningioma, the most common types of brain tumour. This is the first in a series of combined data analyses of head and neck tumours published as part of the internationally coordinated Interphone project.
The authors reported the following conclusion:
Overall, no increase in risk of glioma or meningioma was observed with use of mobile phones. There were suggestions of an increased risk of glioma at the highest exposure levels, but biases and error prevent a causal interpretation. The possible effects of long-term heavy use of mobile phones require further investigation.
Dr Christopher Wild, Director of the International Agency for Research on Cancer (IARC) said: “An increased risk of brain cancer is not established from the data from Interphone. However, observations at the highest level of cumulative call time and the changing patterns of mobile phone use since the period studied by Interphone, particularly in young people, mean that further investigation of mobile phone use and brain cancer risk is merited.”
Michael Milligan, Secretary General of the Mobile Manufacturers Forum said “The absence of increased health risks include long term mobile phone use for more than 10 years. The authors make it clear that the data was insufficient for a clear interpretation of possible risk from self-reported heavy use due to a number of possible errors or biases. For example, the paper notes that there is evidence that people diagnosed with a brain tumour over-reported their past mobile phone use and that ‘recall bias-like this may be more likely if subjects perceive that mobile phone use is associated with brain tumours, as has been widely speculated in the media.”
The Interphone results now need to be considered by independent health authorities, such as the World Health Organization (WHO) and other expert groups to assess their significance, if any, to people’s health.
Mr Milligan added “The mobile industry supports the need for ongoing research. In fact, a number of longer-term studies are already underway such as the COSMOS study, which will follow the health of 250,000 European mobile users for 20-30 years, and several studies are now looking at children and teenagers, including the international MOBI-kids and CEFALO studies and the Australian MoRPhEUS project.”
Although Interphoneis a large and important study, it must be viewed in context as only one of many studies that will be used in the overall cancer-risk assessment to be undertaken by IARC in 2011.
